Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0002p018 | (1) | SRF2015

An E4BP4 knockout model to assess the distribution of uterine Natural Killer cell subsets in mouse pregnancy

Peet Claire Joy , Boulenoaur Selma

Natural Killer cells have been linked to a number of disorders of pregnancy by both mouse studies and association studies in humans, with NK cell dysfunction leading to reduced spiral artery remodelling. However, little research has centred on the importance of the newly divided subsets of uterine Natural Killer cells, some of which appear to develop independently of E4BP4, in spiral artery remodelling, and subsequently fetal growth. Hence, we sought to analyse the dependence ...